Turmeric has proven very useful for heart health. It has significantly improved the ability of the body to carry high loads, researchers report in an article published in the Journal of Applied Physiology.
“We showed that curcumin increases the level of activity of the gene Nrf2, responsible for the fight against oxidants in cells of the heart muscle and other muscles. Such a strategy can significantly improve the quality of life of people suffering from heart problems,” said Wafi Ahmed (Ahmed Wafi) from the University of Nebraska at Omaha (USA).
Curry and many other spices on the basis of turmeric, as recently discovered by scientists, not only improve the appearance and taste of the food, but also have a lot of hidden useful features. For example, a year ago, biologists from the United States found that it can be used to deliver chemotherapy to cancer cells.
Even previously, other research teams have shown that curcumin, the main component of this condiment helps the body fight inflammation and related diseases, and protects from blindness and dementia. On the other hand, many researchers believe that there are no beneficial effects from this substance no, since it is almost insoluble in water and not seeping into the bloodstream.
Wafi and his colleagues discovered another useful property of turmeric and revealed the molecular mechanisms of its action on the body, watching as the main active ingredient of this seasoning has an impact on the heart of several mice.
Coronary artery these rodents were sewn in such a way that their left ventricle remained constantly crowded and could not pump through more than half of the volume. Such artificial disturbances in the circulatory system, how to tell the scientists mimicked what takes place in the heart of people suffering from the most common forms of heart failure.
At rest, these violations do not affect a person’s life, however, when even the slightest exertion his heart is overloaded and it gets tired quickly. As many scientists believe today, these problems of the heart can be caused or exacerbated by inflammation.
Following this idea, Wafi and his colleagues checked, as large doses of turmeric will affect the hearts of mice with a “hardwired” artery. For this, they have embedded in their skin a special pump that constantly pumped into their body a small dose of curcumin, and watched the changes in their stamina over the next five months.
As shown by these experiments, Indian spice noticeably improved heart function rodents. They began to pass about 1.5 times more distance on a treadmill than their relatives that received the injections “dummy”, and thus they ran about 20-30% faster.
The reason for this, as the analysis of gene activity in their muscle cells, was that molecules of curcumin increased the activity of the gene Nrf2, responsible for the control of inflammation and oxidants, as well as two other related DNA segments, HO-1 and SOD2.
Interestingly, similar changes occurred in healthy mice who consumed turmeric – they also started to run longer and faster than rodents in the control group. Scientists believe that all of this suggests that turmeric or other activators of the Nrf2 gene can be used to improve heart health and increase stamina of the person.