Grape stems are discarded en masse during the production of wine. We love and produce a lot of wine in Nagano prefecture, and have been hoping to find a positive use for the previously discarded grape stems. Scientists at Shinshu University studied compounds within grape stem extracts and found significant anti-cancer activity on tumor cells.
In this study, compounds from grape stems were isolated, characterized and evaluated for their anti-tumor activities. One of the compounds in particular was found to have induced cell cycle arrest, apoptosis and suppressed the invasive activity of the cancerous prostrate cells. The compound also significantly suppressed the expression of the cancer-promoting gene FABP5.
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