Metabolism of drugs to alleviate mental illness

According to a large Swedish study medicines, which are prescribed for high blood pressure, Diabetes or high cholesterol could help, even in the case of mental disorders such as schizophrenia, bipolar disorder or psychosis: patients that these medications, required fewer hospitalizations due to psychiatric symptoms, and were injured less often.

In the case of drugs, it was high blood pressure agent from the group of calcium channel blockers such as Verapamil or nifedipine, cholesterol-lowering drug from the group of statins and diabetes agents from the group of Biguanides, e.g., Metformin. Scientists from the Swedish Karolinska Institute and the University of Hong Kong found that mentally ill patients who these medicines, less likely to Self-harm or psychiatric admissions-related sick.

Dr. Joseph Hayes of the Psychiatric Department of the University College London says: "Since these drugs are often used, and the Doctors are well known, they should be as a potential means for the psychiatric symptoms investigated further. All three examined groups of Medicinal products are authorised for use, are frequently used are cheap and relatively safe medication. Therefore, they are ideal candidates for an advanced application."

For the study, data from 142.691 people were illnesses with serious psychological, the drugs against hypertension, Diabetes, or high cholesterol values, revenue, and evaluated. The investigated drugs have known effects on the Central nervous system, however, the mechanism of action is not clarified yet.

ZOU